Adipose-derived Stem Cells and Muscle disorders

Stem cell based therapies for the repair and regeneration of various tissues and organs offer a paradigm shift that may provide alternative therapeutic solutions for a number of diseases. This review focuses on skeletal muscle regeneration and repair by adipose-derived stem cells (ASCs) with particular attention to their potential use as a therapy for disorders such as degenerative muscle diseases or skeletal muscle injuries. ASCs can differentiate into skeletal muscle cells in vitro either in co-culture with skeletal myoblasts. In particular, spontaneous fusion of ASCs and subsequent myotube-like formation was observed in early culture passages at high cell density. ASCs have also shown a capacity for myogenic differentiation in vivo.

In a  muscular dystrophy model, ASCs were able to restore muscle function following direct injection into the affected muscle as well as following intravenous systemic administration.

Of great importance is the finding that allogeneic ASCs injected into the damaged muscle were not rejected, even without immunosuppressive therapy. Because human adipose tissue is ubiquitous and easily obtainable in large quantities under local anesthesia with little patient discomfort, it presents an appealing source of stem cells for mesenchymal tissue regeneration and engineering.

The above text is an abstract from the article "The potential for treatment of skeletal muscle disorders with adipose-derived stem cells" by Hiroshi Mizuno.

Browse the full article here.

StemGenex

Adipose Stem Cell Treatment

StemGenex is the only clinic in North America to offer Adipose Stem Cell Treatment.

Adipose Stem Cell Therapy is a way of harnessing the body's own healing mechanisms to repair and regenerate damaged/diseased tissues and organs. The procedure is a safe and painless, outpatient procedure. Many patients actually feel better and experience benefits from administering stem cells right away.

This is medicine we can all feel good about; it uses the patient’s own stem cell which will be harvested from the abdomen fat. Further, there are no issues regarding the body’s acceptance of foreign cells, since the body recognizes them as your own stem cells.

Adipose Stem Cell Therapy has proven to be a powerful cutting-edge medicine providing repair to cells, and the results have been effective for many individuals.

For more information, please visit their website:

http://www.stemgenex.com/